Arthrosamid® Injections for Knee Pain in Bath | Bath Clinic Skip to main content

Arthrosamid® Injections for Knee Pain in Bath

Bath Clinic offers Arthrosamid® Injections for knee pain in Bath and the wider area

Arthrosamid® is a modern treatment option for individuals living with knee osteoarthritis. It consists of a single injection administered directly into the knee joint, using ultrasound guidance to ensure precise placement. The treatment uses a synthetic hydrogel that helps support and cushion the joint, with the aim of easing discomfort and improving mobility.

On this page, you’ll find information about how Arthrosamid® works, what the procedure involves, and what to expect before, during, and after your treatment.

Book online or call 0808 189 5597 today to arrange a consultation with one of our experienced specialists at Bath Clinic.

Arthrosamid® is currently approved for the treatment of knee osteoarthritis. This condition develops when the cartilage that cushions the joint gradually wears down, allowing the bones to come into contact with each other. As a result, this can cause pain, stiffness, swelling, and a reduced range of movement.

While osteoarthritis can occur in other areas such as the hips, hands, and additional joints, Arthrosamid® is at present only indicated for use in the knee.

Arthrosamid® is an intra-articular treatment, meaning it is delivered directly into the knee joint. It contains a non-biodegradable hydrogel that works by thickening the natural lubricating fluid in the joint, known as synovial fluid, while also integrating with the surrounding tissue. This helps to cushion and lubricate the knee, reducing discomfort and supporting improved movement. Because the hydrogel is not broken down by the body, it remains within the joint, providing longer-lasting relief compared to many other injectable treatments.

Its mechanism of action is linked to its ability to enhance the elasticity of the synovial tissue, which in turn contributes to improved pain management.

  • Minimally invasive procedure with a relatively quick recovery time
  • Long-lasting effects, with a single injection potentially providing relief for up to five years
  • Low likelihood of complications or adverse side effects
  • May help delay the need for knee replacement surgery

This treatment is typically recommended for individuals with moderate to severe knee osteoarthritis who have not experienced sufficient relief from lifestyle changes, medication, or physiotherapy. It may also be an effective option for younger patients looking to delay surgery or avoid extended recovery periods.

Arthrosamid® may not be suitable for you if you:

  • Have haemophilia or other bleeding or clotting conditions
  • Are taking anticoagulant (blood-thinning) medication
  • Are pregnant or breastfeeding
  • Have an active infection in or around the knee
  • Have undergone knee arthroscopy within the past six months
  • Have poorly controlled diabetes
  • Are currently undergoing significant dental treatment
  • Have certain autoimmune conditions, such as multiple sclerosis, Addison’s disease, or coeliac disease

It is important to inform your consultant of any existing medical conditions, allergies, or medications before proceeding with treatment.

 

Your consultant will give you full preparation guidance, which will also be outlined in your appointment letter. If you have any questions ahead of your visit, please contact the hospital.

You may be advised to pause certain medications, such as blood thinners, for a few days prior to the injection to help minimise the risk of bleeding.


On arrival, a member of the clinical team will talk you through the procedure and answer any questions you may have. You’ll be asked to sign a consent form to confirm that you understand the treatment and any associated risks.

You may be given antibiotics through a vein (intravenously) to help reduce the risk of infection.

The injection itself usually takes around 15 minutes to complete.

During the procedure:

  • You will be made comfortable in a suitable position
  • The area around your knee will be cleaned thoroughly
  • A local anaesthetic will be used to numb the injection site
  • Using ultrasound guidance, your consultant will carefully administer Arthrosamid® into the joint
  • The needle will then be removed, and a small dressing or plaster applied

Recovery and aftercare

You will be able to go home shortly after the procedure. It’s common to experience mild swelling or discomfort once the anaesthetic wears off, but this should settle fairly quickly. Over-the-counter pain relief, such as paracetamol or ibuprofen, may help if needed.

You can return to normal daily activities straight away, including walking. However, you should avoid strenuous exercise and heavy lifting for a few days following treatment.

You should not drive for at least 24 hours after your injection, so please arrange transport in advance or ask the hospital if assistance is needed.

Most people are able to return to work as soon as they feel comfortable to do so.


Arthrosamid® is regarded as a safe treatment, however, as with any medical procedure, there are potential risks. Your consultant will discuss these with you in detail before your treatment.

Possible side effects may include:

  • Mild pain or swelling at the injection site, which is usually temporary
  • Short-term stiffness or tenderness in the knee
  • In rare cases, a Baker’s cyst (a fluid-filled swelling that develops behind the knee)
  • Allergic reaction, which is very uncommon
  • Joint infection, which is rare and can typically be treated effectively with antibiotics

Is the injection painful? 

 No. A local anaesthetic is used to numb the area. You may feel pressure but not pain. Tell your consultant if you feel discomfort. 

When will I notice results? 

 Some improvement may occur within 24 hours, but most patients feel significant relief within four weeks. Full benefits usually appear between four and twelve weeks. 

Can both knees be treated? 

 Yes. Your consultant will advise the best approach if both knees are affected. 

How long does it last? 

 Studies show Arthrosamid® can provide relief for up to five years

How is it different from hyaluronic acid injections? 

 Both cushion and lubricate the joint, but hyaluronic acid is broken down by the body within months. Arthrosamid® integrates with joint tissue and lasts much longer. 

We provide expert-led care in a comfortable private healthcare setting. As a patient, you can expect:

  • Convenient and flexible appointment times
  • The ability to choose your consultant
  • Tailored treatment plans designed around your needs
  • Transparent, fixed-price packages that include aftercare
  • Flexible payment options to suit you

Book online today or call our team on 0808 189 5597 to arrange your consultation at Bath Clinic.

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